UBA2 antibody

Catalog No. ABIN7119593

The Rabbit Polyclonal anti-UBA2 antibody has been validated for WB and ELISA. It is suitable to detect UBA2 in samples from Human and Mouse.

Quick Overview for UBA2 antibody (ABIN7119593)

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-UBA2 Antibody

Purpose: UBA2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin-like modifier activating enzyme 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for UBA2

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Alternative Name: UBA2

Background:

Synonyms: SUMO-activating enzyme subunit 2|Anthracycline-associated resistance ARX|Ubiquitin-like 1-activating enzyme E1B|Ubiquitin-like modifier-activating enzyme 2|UBA2|SAE2|UBLE1B

Background: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Molecular Weight: 90 kDa

Gene ID: 10054

UniProt: Q9UBT2